Table 2.

The results of multivariable linear regression analysis in patients with williams syndrome and control subjects^a.

	Iris grading
	Grade I		Grade II		Grade III
	β Coefficient (95% CI)	P Value	β Coefficient (95% CI)	P Value	β Coefficient (95% CI)	P Value
LogMAR BCVA	0.03 [−0.06–0.11]	0.543	0.03 [−0.06–0.12]	0.472	0.02 [−0.07–0.11]	0.693
Vessel Density	−2.67 [−4.97–−0.38]	0.024	−3.52 [−6.57–−0.47]	0.025	0.17 [−2.63–2.96]	0.905
Vessel Density-Fovea	−7.20 [−12.41–−2.00]	0.008	−10.20 [−17.12–−3.27]	0.005	−2.15 [−8.48–4.19]	0.496
Foveal Avascular Zone	0.11 [0.01–0.21]	0.033	0.20 [0.07–0.34]	0.005	0.03 [−0.10–0.16]	0.586
Central Macular Thickness	−17.29 [−31.48–−3.11]	0.018	−29.46 [−44.26–−14.66]	<0.001	−21.68 [−37.08–−6.28]	0.007
Fovea Upper Width	98.35 [34.58–162.11]	0.003	127.08 [57.07–197.10]	0.001	36.96 [−32.22–106.15]	0.288
Fovea Lower Width	128.69 [80.60–176.77]	<0.001	132.91 [80.12–185.71]	<0.001	84.30 [32.13–136.47]	0.002
Arterial Outer Diameter	−17.04 [−24.26–−9.82]	<0.001	−7.48 [−15.31–0.36]	0.061	−20.04 [−27.72–−12.36]	<0.001
Arterial Inner Diameter	−15.55 [−22.09–−9.00]	<0.001	−6.26 [−13.37–0.84]	0.082	−18.16 [−25.13–−11.19]	<0.001
Arterial Vessel Wall	−0.81 [−1.75–0.14]	0.091	−0.85 [−1.87–0.18]	0.102	−0.93 [−1.93–0.08]	0.069
Venous Outer Diameter	−11.00 [−18.73–−3.26]	0.007	−9.39 [−18.60–−0.17]	0.046	−21.84 [−30.89–−12.80]	<0.001
Venous Inner Diameter	−12.77 [−21.21–−4.33]	0.004	−7.47 [−17.53–2.59]	0.141	−26.05 [−35.93–−16.18]	<0.001
Venous Vessel Wall	1.01 [−0.37–2.39]	0.147	−0.73 [−2.37–0.91]	0.373	0.66 [−0.96–2.27]	0.413

logMAR logarithm of the Minimum Angle of Resolution, BCVA best corrected visual acuity, CI confidence interval.

^aAdjusting for Age and Gender, subjects with iris grade 0 were used as controls.