Table 1.
Patient Characteristics and CMR Hemodynamics.
All Patients (N = 122) | SLV (N = 67) | SRV (N = 55) | p-value | |
---|---|---|---|---|
Age at Fontan (years) | 3.4 ± 1.1 | 3.5 ± 1.2 | 3.4 ± 0.9 | 0.643 |
Age at CMR (years) | 12.7 ± 4.7 | 14.4 ± 4.1 | 10.6 ± 4.4 | < 0.001 |
Sex (Female %) | 54 (44.2%) | 35 (52.2) | 19 (34.5) | 0.076 |
BSA (m2) | 1.4 ± 0.4 | 1.5 ± 0.3 | 1.2 ± 0.4 | < 0.001 |
Lateral tunnel | 19 (15.6%) | 9 (13.4%) | 10 (18.2%) | 0.614 |
Extra cardiac conduit | 103 (84.4%) | 58 (86.6%) | 45 (81.8%) | 0.639 |
EDVi (ml/m2) | 91 (74—112) | 81 (67—96) | 101 (88—131) | < 0.001 |
ESVi (ml/m2) | 47 (34—60) | 39 (31—52) | 54 (45—75) | < 0.001 |
EF (%) | 48 ± 8 | 51 ± 7 | 45 ± 9 | < 0.001 |
CI (L/min/m2) | 3.5 ± 1.3 | 3.2 ± 1.0 | 3.9 ± 1.5 | 0.003 |
Heart rate | 77 ± 20 | 76 ± 16 | 77 ± 25 | 0.758 |
Peak GCS (%) | − 13.5 ± 3.5 | − 15.4 ± 3.0 | − 11.1 ± 2.6 | < 0.001 |
Peak GLS (%) | − 12.6 ± 3.1 | − 13.4 ± 3 | − 11.7 ± 2.8 | 0.002 |
All data reported as mean ± SD or as median with corresponding IQR.
CMR cardiac magnetic resonance, BSA body surface area, EDVi end-diastolic volume index, ESVi end-systolic volume index, EF ejection fraction, CI cardiac index, GCS global circumferential strain, GLS global longitudinal strain. p-values represent unpaired t-test or Mann–Whitney test.