Table 2.
Genetic features of CM patients.
Patient No. | Molecular feature | Surgery | Outcome |
---|---|---|---|
1 | BRAF V600E mutation | Eye-sparing | Follow-up |
2 | BRAF V600E mutation | Orbital exenteration | Brain and liver metastasis; Death |
3 | BRAF V600E mutation | Eye-sparing | Follow-up |
4 | BRAF V600E mutation | Eye-sparing | Follow-up |
5 | BRAF V600E mutation | Eye-sparing | Lung metastasis |
6 | NRAS Q61R mutation | Orbital exenteration | Follow-up |
7 | NRAS Q61R mutation | Orbital exenteration | Follow-up |
8 | NRAS Q13R mutation | Eye-sparing | Follow-up |
9 |
NRAS Q61R mutation NF1 Q1370X mutation TERT P265S mutation |
Orbital exenteration | Follow-up |
10 |
KIT L572P mutation NF1 c.655-2 A > T mutation TERT S797F mutation |
Eye-sparing | Follow-up |
11 | NF1 2122_2124del | Orbital exenteration | Follow-up |
16 patients’ genetic data were available; 11 of them had BRAF, NRAS, NF1, KIT or TERT mutation.