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. 2023 Jul 24;13:11967. doi: 10.1038/s41598-023-39168-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The correlation matrix of gut microbial β-glucuronidase activity with estradiol and testosterone levels. (A) PCOS group shows a positive association between testosterone level and β-glucuronidase activity with r = 0.10 and p = 0.64. (B) Control group shows a positive association between testosterone and β-glucuronidase activity with r = 0.37 and p = 0.06. (C) PCOS group shows a positive correlation between β-glucuronidase activity and estradiol with r = 0.3 and p = 0.17. (D) The control group shows a negligible positive correlation between β-glucuronidase activity and estradiol level with r = 0.05 and p = 0.80.