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. 2023 Jul 24;13:11967. doi: 10.1038/s41598-023-39168-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation matrix of gut microbial β-glucosidase activity with estradiol and testosterone level. (A) PCOS group shows a positive correlation between β-glucosidase activity and estradiol with r = 0.48 and p = 0.01. (B) The control group shows a negative association between estradiol level and β-glucosidase activity with r = -0.25 and p = 0.22. (C) PCOS group shows a negative correlation between β-glucosidase activity and testosterone level r = − 0.14 and p = 0.52. (D) Control group shows a positive association between testosterone and β-glucosidase activity with r = 0.17 and p = 0.39.