Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 24;13:11950. doi: 10.1038/s41598-023-37300-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The role of the m5Cscore in predicting immunotherapeutic benefits. (A) The relationship between the m5Cscore and TMB. (B) The relationship between the m5Cscore and MSI. (C) PD-L1 expression and (D) PD-1 expression between the distinct high and low m5Cscore groups in the meta-CRC cohort. (E,F) Tumor somatic mutations were assessed in individuals in the high and low m5Cscore groups (shown in the left and right waterfall plots, respectively). The individual patients are represented in each column. The upper bar plot is TMB. The mutation frequency in each regulator is shown on the right. The proportion of each variant type is shown on the right bar plot. The fraction of conversions in each patient is shown in the stacked bar plot below.