Table 1.
Characteristics of 519,152 participants by use of a proton pump inhibitors (PPI)
| Exposure | No PPI* | PPI* |
|---|---|---|
| Number of periods | 507,016 (62.2%) | 307,709 (37.8%) |
| Person-years | 3,780,049 (80.0%) | 943,143 (20.0%) |
| Sex | ||
| Male | 256,625 (50.6%) | 149,752 (48.7%) |
| Female | 250,391 (49.4%) | 157,957 (51.3%) |
| Age (interquartile range), years | ||
| < 50 | 89,324 (14.0%) | 38,565 (10.8%) |
| 50–69 | 205,805 (32.3%) | 109,133 (30.7%) |
| ≥ 70 | 341,861 (53.7%) | 208,142 (58.5%) |
| Calendar year (interquartile range) | ||
| 2005–2010 | 468,549 (39.8%) | 180,741 (33.0%) |
| 2010–2014 | 411,869 (35.0%) | 203,777 (37.3%) |
| 2015–2019 | 297,334 (25.2%) | 162,509 (29.7%) |
| Smoking-related diseases | 91,375 (16.1%) | 65,459 (19.4%) |
| Number of pneumonias, mean (standard deviation) | ||
| 0.94 (0.76) | 0.64 (0.86) | |
*Patients can contribute to both unexposed and exposed periods multiple times and in time-variant parameters (age, calendar year, smoking-related diseases)