Table 2.
Exposure | Pneumonias (number) |
Crude IRR (95% CI) |
Adjusted IRR (95% CI) * |
---|---|---|---|
No PPI | 479,103 | 1.00 (reference) | 1.00 (reference) |
PPI | 197,983 | 2.44 (2.42–2.47) | 1.73 (1.71–1.75) |
No PPI | |||
Baseline | 437,599 | 1.00 (reference) | 1.00 (reference) |
60 days prior to PPI | 41,504 | 4.25 (4.20–4.31) | 3.64 (3.59–3.68) |
PPI | |||
First month (1–30 days) | 18,809 | 3.01 (2.96–3.06) | 2.59 (2.55–2.63) |
Second and third month (31–90 days) | 27,570 | 2.69 (2.65–2.73) | 2.25 (2.22–2.28) |
After the third month (> 90 days) | 151,604 | 3.50 (3.46–3.54) | 2.20 (2.17–2.23) |
*Adjusted for age and calendar year