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. 2023 Apr 20;27(7):1473–1485. doi: 10.1007/s11605-023-05626-8

Table 1.

Characteristics of the included primary studies identified in the systematic review that reported on diagnostic outcomes

First author Year Location Study type Study duration (months) Total patients Mean age (range) (years) Proportion of women Number of operative patients Reference Standard Reference standard positive appendicitis
S Serinsoz30 2021 Turkey Retrospective, centre unknown 24 70 32 (11–71) 63% 40 Surgical results; unclear for non-operated patients 37/70 (53%)
G Islam31 2021 India Prospective, single-centre 18 67 24 (6–70) 37% 39 Histopath; or clinical follow-up 45/67 (67%)
A Inoue32 2019 Japan Retrospective, single-centre 10 51 35 (6–90) 53% 25 Surgery; or clinical follow-up and CT 35/51 (69%)
M Repplinger33 2018 USA Prospective, single-centre 30 198 32 (12–81) 58% Not reported Expert panel; Histopath or clinical follow-up 64/198 (32%)
S Byott34 2016 England Prospective, single-centre 60 468 Median 27 (7–59) 74% 116 Surgical, histological, and clinical follow-up 38/468 (8%)
I Petkovska35 2016 USA Retrospective, single-centre 24 253 Not reported Not reported Not reported Expert panel; surgical results; or clinical follow-up 35/253 (14%)
H Gielkens36 2016 Netherlands Prospective, single-centre 18 112 Median 22 (12–55) 100% 51 Histopath; or clinical follow-up 29/112 (26%)
M Leeuwenburgh37 2014 Netherlands Prospective, multi-centre 6 223 35 (18–84) 62% 128 Expert panel; surgical findings, histopath, and clinical-follow-up 117/223 (52%)
S Avcu38 2013 Turkey Prospective, single-centre 12 55 36 (17–83) 43% 40 Histopath; unclear for non-operated patients 40/55 (73%)
First Author Year Location Study type Study duration (months) Total patients Mean age (range) (years) Proportion of women Number of operative patients Reference Standard Reference standard positive appendicitis
B Zhu39 2012 China Prospective, single-centre 24 41 42 (range not reported) 56% 41 Surgery/histopath 36/41 (88%)
E Inci40 2011 Turkey Prospective, single-centre 11 119 27 (17–72) 36% 92 Histopath; unclear for non-operated patients 79/119 (66%)
E Chabanova41 2011 Denmark Prospective, single-centre Not reported 48 37 (18–70) 60% 48 Surgery/histopath 30/48 (63%)
L Cobben42 2009 Netherlands Prospective, single-centre 22 138

Not reported

(6–80)

58% 64 Histopath; or clinical follow-up 62/138 (44.9%)
A Singh43 2008 USA Retrospective, multi-centre 72 67 34 (11–69) 91% Not reported Surgical results; unclear for non-operated patients 12/67 (18%)
N Nitta44 2005 Japan Prospective, single-centre Not reported 37 37 (16–69) 51% 31 Surgery/histopath; clinical follow-up 29/37 (43%)
L Incesu46 1997 Turkey Prospective, single-centre 22 60 20 (14–71) 55% 39 Surgery/histopath; or clinical follow-up 34/60 (57%)