Table 1.
Sample characteristics of probands and siblings
| Probands N = 256 | Siblings N = 380 | |
|---|---|---|
| Sociodemographics | ||
| Age (years), M (SD) | 48.52 (13.10) | 50.46 (13.25) |
| Female gender, % | 73.4 | 55.0 |
| Education (years), M (SD) | 13.42 (2.99) | 13.17 (3.22) |
| Low income, % | 52.9 | 47.5 |
| Life adversity and lifestyle | ||
| Early life | ||
| Childhood trauma, M (SD) | 38.59 (10.64) | 37.18 (9.54) |
| Poor parental bonding—maternal, M (SD) | 31.70 (8.88) | 30.63 (8.26) |
| Poor parental bonding—paternal, M (SD) | 31.90 (8.57) | 31.20 (8.26) |
| Recent life | ||
| Unemployment, % | 36.7 | 29.6 |
| Living alone, % | 28.9 | 20.8 |
| Being single, % | 25.4 | 21.3 |
| Small social network, % | 38.6 | 24.5 |
| Negative life events—independent, M (SD) | 0.30 (0.60) | 0.45 (0.67) |
| Negative life events—dependent, M (SD) | 0.21 (0.54) | 0.27 (0.59) |
| Smoking status, % | 20.3 | 24.3 |
| Hazardous alcohol use, % | 30.8 | 28.5 |
| Physical activity, M (SD) | 3.58 (2.92) | 4.15 (3.48) |
| Mental health | ||
| Current depressive symptom severity, M (SD) | 16.45 (10.49) | 13.15 (9.72) |
| Current anxiety symptom severity, M (SD) | 9.22 (8.11) | 5.73 (6.09) |
| Current depressive and/or anxiety disorder diagnosis, % | 37.5 | 26.8 |
| Lifetime depressive and/or anxiety disorder diagnosis, % | 100.0 | 50.3 |
Sample sizes vary slightly due to marginally missing data on psychosocial risk factors (Supplementary Table 1)
M mean, SD standard deviation