Table 1.
Clinical features of PSC patients and controls
| PSC with IBD (n = 36) | PSC without IBD (n = 20) | CCC (n = 32) | IgG4-SC (n = 14) | PBC (n = 39) | AIH (n = 15) | Collagen disease (n = 27) | Healthy control (n = 23) | |
|---|---|---|---|---|---|---|---|---|
| Age | ||||||||
| Range | 19–74 | 22–80 | 52–85 | 43–84 | 35–86 | 24–90 | 20–78 | 20–78 |
| Median | 39.0 | 42.5 | 70.0 | 70.0 | 66.0 | 69.0 | 56.0 | 56.0 |
| Average | 39.7 | 46.0 | 70.9 | 69.7 | 65.0 | 62.7 | 55.9 | 55.9 |
| Sex male (%) | 25 (69.4) | 13 (65.0) | 19 (59.4) | 11 (78.6) | 6 (15.4) | 1 (6.7) | 8 (29.6) | 14 (60.9) |
| Age of diagnosis | ||||||||
| Range | 11–66 | 18–76 | ||||||
| Median | 27.0 | 39.0 | ||||||
| Average | 30.1 | 41.0 | ||||||
| ALPa (U/L) | ||||||||
| Range | 57–1000 | 69–666 | ||||||
| Median | 277.0 | 264.0 | ||||||
| Average | 323.0 | 275.0 | ||||||
| PMS (%) | ||||||||
| 0 | 31 (86.1) | |||||||
| 1 | 3 (8.3) | |||||||
| 2 | 1 (2.8) | |||||||
| 3 | 1 (2.8) | |||||||
| > 4 | 0 (0) | |||||||
| Rectal sparing (%) | 16/25 (64) | |||||||
PSC primary sclerosing cholangitis, IBD inflammatory bowel disease, CCC cholangiocellular carcinoma, IgG4-SC IgG4-related sclerosing cholangitis, PBC primary biliary cholangitis, AIH autoimmune hepatitis, ALP alkaline phosphatase, PMS partial Mayo score
aThe normal range of ALP is 38–113 U/L