Table 2.
Comparison of clinical characteristics between patients with anti-integrin αvβ6 antibody-positive and antibody-negative PSC
Positive n = 49 | Negative n = 6 | P value | |
---|---|---|---|
Age | 0.48 | ||
Mean | 40.8 | 45.3 | |
Median | 40 | 50 | |
Sex | 0.07 | ||
Male | 36 (73.4%) | 2 (33.3%) | |
ALPa U/L | 0.17 | ||
Mean | 321.5 | 190.7 | |
Median | 277 | 232 | |
T-Bilb mg/dl | 0.30 | ||
Mean | 4.8 | 1.4 | |
Median | 1.7 | 0.9 | |
CRPc mg/dl | 0.22 | ||
Mean | 1.5 | 0.4 | |
Median | 0.8 | 0.1 | |
IBD | 0.02 | ||
Presence | 34 (69%) | 1 (17%) |
PSC primary sclerosing cholangitis, ALP alkaline phosphatase, T-Bil total-bilirubin, CRP C-reactive protein, IBD inflammatory bowel disease
aThe normal range of ALP is 38–113 U/L
bThe normal range of T-Bil is 0.3–1.3 mg/dL
cThe normal range of CRP is 0–0.2 mg/dL