Fig. 2. Preliminary density functional theory (DFT) calculations on the racemization processes and condition optimization.
a Activation energy barrier for axial rotation of 3-bromo-2,1-borazaronaphthalene 1a. b Activation energy barrier for axial rotation of 3-bromo-naphthalene 1a-C. c Activation energy barrier for axial rotation of 3-Pd-2,1-borazaronaphthalene via a TS featuring tetracoordinate boron geometry, TS-Pd. d Condition optimization for palladium-catalyzed dynamic kinetic asymmetric cross-coupling.