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. 2023 Jul 11;11:1139496. doi: 10.3389/fpubh.2023.1139496

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Copyright © 2023 Mujwara, Kintzle, Di Domenico, Busby and Bottà.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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One-way sensitivity analysis of CardioriskSCORE compared to Standard-WHP. This figure shows results from the one-way sensitivity analysis for CardioriskSCORE compared to the Standard-WHP. Variation in parameter values did not change conclusions in the base case findings as indicated with positive incremental net monetary benefit across all parameters. Stain effectiveness on CAD had the highest impact on the findings. CAD, coronary artery disease; CAD-PRS, polygenic risk score for coronary artery disease; EV, expected value.