Table 2.

Results for the base case analysis in 5 years.

Strategy	Costs (US$)*	Incremental costs	QALYs*	QALYs gained	ICER
CardioriskSCORE	29,668 24,197–35,591	-	4.507 4.435 –4.578	-	Dominant
Standard-WHP	29,722 24,222–35,669	53	4.506 4.434 –4.577	−0.001	-
No-WHP	30,243 24,561–36,412	575	4.502 4.429 –4.574	−0.005	-

PCE, Pooled cohort equation; PRS, polygenic risk score; QALYs, quality-adjusted life years; ICER, incremental cost-effectiveness ratio; CAD, coronary artery disease; No-WHP, no wellness health program. ^*Intervals represent 2.5th to 97.5th percentiles. This table shows base case cost-effectiveness analysis results for a 5-year time horizon in a cohort of 50-year-old employees. Compared to Standard-WHP and No-WHP alternatives, CardioriskSCORE had higher mean QALYs (0.001, 0.005) and lower mean costs ($53, $575) per employee.