REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti- lipocalin-2 antibody produced in rat	Abcam	Ab70287; RRID:AB_2136473
Anti- cluster of differentiation 31 antibody produced in goat	R&D systems	AF3628; RRID:AB_2161028
Anti- glial fibrillary acidic protein antibody produced in rabbit	Dako	Z0334; RRID:AB_10013382
Anti- aquaporin 4 antibody produced in rabbit	BosterBio	BSBTPB9475; RRID:AB_2039734
Anti- microtubule-associated protein-2 antibody produced in mouse, clone HM-2	Sigma-Aldrich	M4403; RRID:AB_477193
Anti- myelin basic protein antibody produced in mouse, clone SMI-94	BioLegend	836504; RRID:AB_2616694
Alexa Fluor 488 donkey anti-rat IgG (H+L)	Life technologies	A21208; RRID:AB_2535794
Alexa Fluor 594 donkey anti-rabbit IgG (H+L)	Invitrogen	A21207; RRID:AB_141637
Alexa Fluor 647 donkey anti-goat IgG (H+L)	Invitrogen	A21447; RRID:AB_141844
Goat anti-rabbit IgG (H+L), biotinylated	Vector Laboratories	BA-1000; RRID:AB_2313606
Horse anti-goat IgG (H+L), biotinylated	Vector Laboratories	BA-9500; RRID:AB_2336123
Horse anti-mouse IgG (H+L), biotinylated	Vector Laboratories	BA-2001; RRID:AB_2336180
Peroxidase labelled goat anti-rabbit IgG (H+L)	Vector Laboratories	PI-1000; RRID:AB_2336198
Bacterial and virus strains
Staphylococcus epidermidis 1457	Michael Otto’s laboratory68
Biological samples
Preterm infant blood samples	Randomized controlled trial MegaDonnaMega	ClinicalTrials.gov Identifier: NCT03201588)
Chemicals, peptides, and recombinant proteins
Pentobarbital	APL	Cat#338327
Histofix	Histolab products AB	Cat#01000
Isopentane	Sigma Aldrich, Darmstadt, Germany	PHR1661
DAPI	Invitrogen	P36935
Antifade Mounting Medium	Vector Laboratories	Cat#00840-05
Target retrieval solution	Dako S1700, Glostrup, Denmark	S1699
3,3′-diaminobenzidine (DAB) solution	DAB EASY tablets, ACROS Organics™	AC328005000
Thionin solution	Sigma	T3387
Tryptan Blue	Sigma Aldrich,	Cat#302643
RLT Lysis buffer	Qiagen	Cat# 79216
miRNeasy Micro Kit	Qiagen	Cat# 217084
RNA library and transcriptome sequencing	Novogene Co., LTD (Cambridge, UK).	https://en.novogene.com/
Critical commercial assays
ABC solution	VECTASTAIN Elite ABC HRP Kit	PK-6100
Pierce™ BCA Protein Assay Kit	Thermo Fischer Scientific
Tandem Mass Tag (TMT-11plex) reagents	Thermo Fischer Scientific
Dionex Ultimate 3000 UPLC system	Thermo Fischer Scientific
QuantiTect Reverse Transcription Kit	Qiagen
Fast SYBR master mix	Qiagen
lcn2 primers	Qiagen	QT00113407
NGAL ELISA kit	Abcam	ab199083
Deposited data
Dataset identifier PXD041926	ProteomeXchange, PRIDE database	PubMed ID: 34723319
Experimental models: Organisms/strains
C57Bl/6J wild-type mice	Janvier Labs/ Charles River Laboratories
GFAP-/- VIM -/-	University of Gothenburg Milos Pekny's laboratory
Software and algorithms
newCAST software	Visiopharm, Hørsholm, Denmark	https://visiopharm.com/visiopharm-digital-image-analysis-software-features/stereology/
Fiji software version 1.53c
R software (version 1.4.1106)	https://www.r-project.org/	N/A
Perseus software	http://coxdocs.org/doku.php?id=perseus:start
Cytoscape software (version 3.8.2)	Shannon, P., et al., 200369	https://cytoscape.org/
DESeq2 v1.32.0	Love, M.I et al., 201470	https://bioconductor.org/packages/release/bioc/html/DESeq2.html
WGCNA R package v1.68	Langfelder, P et al., 201431	https://horvath.genetics.ucla.edu/html/CoexpressionNetwork/Rpackages/WGCNA/
Cytoscape StringApp	Doncheva, N.T et al., 201967	https://apps.cytoscape.org/apps/stringapp
Enrichment Map	Merico, D et al. 201022	https://apps.cytoscape.org/apps/enrichmentmap
Cyto-Hubba plug-in	Chin, C.H et al., 2014 71	https://apps.cytoscape.org/apps/cytohubba
Proteome Discoverer version 2.4	Thermo Fisher Scientific
Mascot search engine v. 2.5.1	Matrix Science, London, UK
IPA	Qiagen
GraphPad Prism 8	La Jolla, California, USA