Grade	Evidence
A	At least one meta-analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or A body of evidence consisting principally of studies rates as 1+, directly applicable to the target population, and demonstrating overall consistency of results
B	A body of evidence including studies rated as 2++, directly applicable to the target population, and demonstrating overall consistency of results, or Extrapolated evidence from studies rated as 1++ or 1+
C	A body of evidence including studies rates as 2+, directly applicable to the target population and demonstrating overall consistency of results, or Extrapolated evidence from studies rated as 2++
D	Evidence level 3 or 4 or Extrapolated evidence from studies rated as 2+
☑	Good practice points – Recommended best practice based on the clinical experience of the guidelines development group

RCT = Randomised controlled trial.