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. 2023 Jun 30;26(7):107231. doi: 10.1016/j.isci.2023.107231

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© 2023 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

TSA treatment leads to a genomic redistribution of H3K9ac, H3K27ac and H3K27me3

(A) Scheme representing the strategy used in Min6 cells.

(B) Number of H3K9ac, H3K27ac and H3K27me3 peaks in vehicle- and TSA-treated Min6 cells.

(C–F) H3K9ac, H3K27ac and H3K27me3 signal in conserved active promoters (C), bivalent promoters (D), poised enhancers (E) and active enhancers (F) in vehicle- and TSA-treated Min6 cells. Heatmaps and mean signals centered on TSS +/−2.5 kb are represented.

See also Figures S3 and S4.