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Synergistic and Time-kill effect on carbapenemase-producing K. pneumoniae clinical isolates (n = 29)
(A) Synergistic, and Time-kill data for (B) Ca-EDTA + ceftazidime/avibactam, (C) Ca-EDTA +aztreonam, (D) aztreonam + ceftazidime/avibactam. All experiments in (A) and (B) was performed as three biologically independent experiments, and the mean ± s.d. is shown. p values were determined using an unpaired, two-tailed Student’s t test.
