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. 2023 Jun 28;26(7):107215. doi: 10.1016/j.isci.2023.107215

Table 1.

Clinical characteristic, carbapenems susceptibility, phenotype, and gene pattern of K. pneumoniae clinical isolates (n = 29)

No. Specimen Sex Age (Years) Carbapenems susceptibility test
Phenotype of
Gene pattern Pattern of entire of bla gene by sequencing
IMP MEM ETP DOR Carbapenemases MBLs KPC Biofilm formation category
U17 Urine R R R NT + + IMP IMP-14a Strong
U22 Urine R R R NT + + IMP IMP-14a Strong
U35 Urine R R R NT + + IMP IMP-14a Strong
V17 Urine R R R NT + + IMP IMP-14a Strong
385 Urine Male 70 R R R R + + IMP IMP-14a Strong
593 Urine Male 70 R R R R + + NDM NDM-1 Moderate
U12 Urine Male R R R NT + + NDM NDM-1 Moderate
U27 Urine R R R NT +/w + NDM NDM-1 Moderate
U9 Urine R R R NT + + NDM NDM-1 Strong
52 Urine R R R NT +/w + NDM NDM-1 Moderate
383 Urine Male 66 R R R R +/w + NDM NDM-1 Strong
480 Bile Male 59 R R R R + + NDM NDM-1 Strong
492 Urine Female 91 R R R R + + NDM NDM-1 Strong
631 Urine Male 88 R R R R + + NDM NDM-1 Moderate
503 Sputum Male 81 R R R R + OXA-48 OXA-181 Moderate
454 Bile Male 73 R R R R + + OXA-48+NDM OXA-181+NDM-5 Strong
614 Endotracheal aspirate Male 1 month R R R R + OXA-48 OXA-232 Strong
477 Bile Female 45 R R R R + OXA-48 OXA-232 Strong
500 Blood Male 63 R R R R + OXA-48 OXA-232 Strong
605 Pus, Wound Male 74 R R R R + + OXA-48+NDM OXA-232+NDM-1 Strong
601 Sputum Male 89 R R R R + + OXA-48+NDM OXA-232+NDM-1 Moderate
628 Sputum Male 83 R R R R + + OXA-48+NDM OXA-232+NDM-1 Moderate
460 Corneal scraping Male 67 R R R R + + OXA-48+NDM OXA-232+NDM-1 Strong
495–1 Biopsy. Tissue, Autopsy Male 69 R R R R + +/− OXA-48+NDM OXA-232+NDM-1 Strong
498 Urine Female 35 R R R R + + OXA-48+NDM OXA-232+NDM-1 Moderate
622 Urine Male 88 R R R R + + OXA-48+NDM OXA-232+NDM-1 Strong
632 Urine Female 83 R R R R + + OXA-48+NDM OXA-232+NDM-1 Strong
478 Biopsy. Tissue, Autopsy Male 69 I I I S + OXA-48 OXA-48 Moderate
633 Urine Female 46 R R R R + OXA-48 OXA-48 Strong

IMP, Imipenem; MEM, Meropenem; ETP, Ertapenem; DOR, Doripenem; S, Susceptible; I, Intermediate; R, Resistant; NT, not tested; +, positive; -, negative; +/−, CAEDTA disk synergy positive but CAEDTA combination disk negative; +/w, weakly positive.