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Effect of cytokine inhibition on IL-1β-stimulation of [3H]thymidine into gastric epithelial cells AGS cells were treated with 10 ng/ml IL-1β for 24 hours plus either interleukin-1 receptor antagonist (IL-1RA 500 ng/ml), neutralising anti-IL-8 antibody (10 μg/ml) or neutralising anti-GM-CSF antibody (5 μg/ml). DNA synthesis was assessed by [3H]thymidine incorporation. Results expressed as means ± standard deviation. *P < 0.01 vs. IL-1β stimulation in absence of inhibitor.
