图 5.

I4VO模型术后视网膜与视束组织病理学情况

Histopathology of the retina and optic tract after modeling. A: HE staining of the retinal tissue within 28 days after modeling (×400, scale bar: 50 μm). B: Retina thickness. C: RPE thickness. D: PL thickness. E: ONL thickness. F: OPL thickness. G: INL thickness. H: IPL thickness. I: GCL/NFL thickness. J: RGCs per 500 μm in the GCL. K: Histopathology of optic tract after I4VO model within 28 days after molding (× 400, scale bar: 50 μm). RPE: Retinal pigment epithelium; PL: photoreceptor layer; ONL: outer nuclear layer; OPL: outer plexiform layer; INL: inner nuclear layer; IPL: inner plexiform layer; GCL/NFL: ganglion cell layer/nerve fiber layer. Data are presented as Mean±SD (Sham group: n=8; I4VO-D1: n=8; I4VO-D3: n=7; I4VO-D7: n=6; I4VO-D14: n=6; I4VO-D28: n=6).