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. 2023 Jul 11;14:1205741. doi: 10.3389/fimmu.2023.1205741

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Copyright © 2023 Li, Long, Nong, Zheng, Meng and Zhu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of CRGs expression and immune cell infiltration between molecular subtypes of TB. (A) Distinct CRGs expression profiles were observed between Cluster 1 and Cluster 2. (B)The expression of 13 CRGs between two clusters was presented in the boxplot. The expression of NFE2L2, NLRP3, SLC31A1, LIPT1, DLD, DLAT, MTF1, GLS, and DBT was significantly upregulated in Cluster 2 (C) The difference in the abundance of 22 infiltrating immune cell types between the two clusters. (D) The differences in immune infiltration between control and TB groups are shown in a boxplot. The abundance of M0 macrophages, eosinophils, and neutrophils was significantly increased. *p<0.05, **p<0.01, ***p<0.001.