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Fig. 2. (A) ROS generation from CyI-S-diCF3 (10 μM) with or without GSH (100 μM) using DPBF as a probe under 808 nm irradiation (0.33 W cm−2, 3 min). (B) Compare the attenuation of the maximum absorbance of DPBF at 60 s of irradiation with 808 nm laser through various power density. Data are presented as the mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. (C) GSH-depletion abilities in the absence and presence of CyI-S-diCF3 (4.0 μM) with indicator DTNB, respectively. (D) Schematic illustration of oxidative stress strengthened by GSH depletion and enhanced singlet oxygen production efficiency.