Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 11;16:1205265. doi: 10.3389/fnmol.2023.1205265

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Ye, Tang, Miao, Gong, Shu, Feng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Functional properties of the homomericKCNQ2 variants. (A) Macroscopic current traces recorded in CHO cells transfected with KCNQ2 variants (3μg) in homomeric configuration. Current scale, 250 pA; time scale, 200 ms. (B) Mean current densities of KCNQ2 channel at +40 mV in the homozygous state. (C) Current–voltage relationships of the KCNQ2 homomeric channel were determined from tail current amplitudes. Lines represent fits of a Boltzmann function. (D) Differences in activation of V_0.5 were determined for the KCNQ2 channel expressed in the homozygous state (n = 8–15). Statistically significant differences *p < 0.05 versus WT KCNQ2.