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. 2023 Jul 11;15:1184609. doi: 10.3389/fnagi.2023.1184609

TABLE 3.

Results of multiple linear regression analyses for the associations between PASE categories and cognition.

Total score Episodic memory score Non-memory score
β p β p β p
Overall
Model 1 a
High 0.124 0.032 0.140 0.007 0.067 0.335
Medium 0.075 0.201 0.075 0.152 0.079 0.264
Low Reference Reference Reference
Model 2 b
High 0.128 0.028 0.146 0.005 0.068 0.338
Medium 0.066 0.256 0.067 0.204 0.074 0.302
Low Reference Reference Reference
APOE4-negstive
Model 1 a
High 0.043 0.867 0.117 0.584 −0.179 0.520
Medium −0.090 0.706 −0.099 0.620 −0.194 0.455
Low Reference Reference Reference
Model 2 b
High 0.107 0.634 0.098 0.637 −0.078 0.775
Medium −0.208 0.348 −0.188 0.359 −0.366 0.186
Low Reference Reference Reference
APOE4-positive
Model 1 a
High 0.143 0.022 0.140 0.016 0.095 0.206
Medium 0.091 0.146 0.110 0.060 0.098 0.198
Low Reference Reference Reference
Model 2 b
High 0.147 0.018 0.148 0.011 0.097 0.207
Medium 0.096 0.122 0.113 0.054 0.101 0.192
Low Reference Reference Reference
Young-old age (65–70 years)
Model 1 a
High 0.114 0.194 0.077 0.349 0.074 0.518
Medium 0.089 0.335 0.100 0.259 0.182 0.138
Low Reference Reference Reference
Model 2 b
High 0.147 0.107 0.088 0.313 0.108 0.365
Medium 0.068 0.476 0.082 0.368 0.171 0.175
Low Reference Reference Reference
Old-old age (> 70 years)
Model 1 a
High 0.109 0.179 0.202 0.005 0.023 0.805
Medium 0.009 0.917 0.061 0.402 −0.032 0.745
Low Reference Reference Reference
Model 2 b
High 0.099 0.223 0.190 0.008 0.020 0.834
Medium −0.003 0.970 0.042 0.559 −0.035 0.727
Low Reference Reference Reference

PASE, physical activity scale for the elderly; APOE4, apolipoprotein ε4; GDS, geriatric depression scale; VRS, vascular risk score.

a Adjusted for age, sex, APOE4, education, clinical diagnosis, GDS, VRS, alcohol intake, and dietary pattern.

b Adjusted for covariates in Model 1 plus blood nutritional markers.