Table 1.
Baseline characteristics
| Baseline characteristic | N = 272 |
|---|---|
| Age, y | 75.36 (± 8.75) |
| Male | 172 (63.2) |
| Body mass weight, kg/m2 | 28.19 (± 6.02) |
| Atrial fibrillation type | |
| Permanent or persistent | 153 (56.2) |
| Paroxysmal | 118 (43.4) |
| Unknown | 1 (0.4) |
| History of LAA thrombus | 13 (4.8) |
| Hypertension | 203 (74.6) |
| Dyslipidemia | 176 (64.7) |
| Diabetes | 90 (33.1) |
| Smoking history | |
| Current smoker | 22 (8.1) |
| Former smoker | 120 (44.1) |
| Coronary artery disease | 104 (38.2) |
| Prior percutaneous coronary intervention | 54 (19.9) |
| Coronary artery bypass grafting | 40 (14.7) |
| Chronic heart failure | 70 (25.7) |
| Left ventricular ejection fraction < 40% | 53 (19.5) |
| Prior valve surgery | 21 (7.7) |
| Prior stroke | 80 (29.4) |
| Prior transient ischemic attack | 40 (14.7) |
| Prior systemic embolization | 11 (4.0) |
| Prior atrial fibrillation ablation | 14 (5.1) |
| Peripheral artery disease | 19 (7.0) |
| Pacemaker | 55 (20.2) |
| Intracardiac defibrillator | 11 (4.0) |
| Creatinine, μmol/L | 106.76 (± 46.59) |
| Laboratory data | |
| Estimated GFR, mL/min per 1.73 m2 | 59.37 (± 20.06) |
| Hemoglobin baseline, g/dL | 125.26 (± 19.94) |
| Indications for LAA closure | |
| CHA2DS2-VASc | 4.35 (± 1.64) |
| HAS-BLED score | 3.55 (± 0.94) |
| Previous minor bleeding | 59 (21.7) |
| Previous major bleeding | 219 (80.5) |
| Intracranial | 99 (36.4) |
| Gastrointestinal | 106 (39.0) |
| Retroperitoneal | 4 (1.5) |
| Intraocular | 7 (2.6) |
| Respiratory | 6 (2.2) |
| Urogenital | 8 (2.9) |
Values are n (%), or mean (± standard deviation).
CHA2DS2-VASc, Congestive Heart Failure, Hypertension, Age [≥ 75 Years] [doubled], Diabetes Mellitus, Stroke [doubled], Vascular Disease, Age [65-74] Years, Sex Category [Female]; GFR, glomerular filtration rate; HAS-BLED, Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly [> 65 Years], Drugs/Alcohol Concomitantly; LAA, left atrial appendage.