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. 2023 Jul 3;35:101708. doi: 10.1016/j.tranon.2023.101708

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© 2023 The Authors. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 8 — CVB induces apoptosis, and cell cycle arrest and inhibits the proliferation of PC3 and C4-2 cells. (A, B) Apoptosis assay of CRPC cells after treatment with CVB at different concentrations (0-160 μmol/L, 24 h). The data are presented as the mean ± SD (n = 3); *P < 0.01, **P < 0.001. vs. the control group. (C, D, E and F) Cell cycle assay of PC3 and C4-2 cells after treatment with CVB (80 μmol/L, 24 h). The data are presented as the mean ± SD (n = 3); *P < 0.05. vs. the control group. (G, H) A colony formation assay was used to confirm the growth inhibitory effect of CVB (0-160 μmol/L, 3 h). The data are presented as the mean ± SD (n = 3); *P < 0.05.vs. the control group.