Fig. 6.
In vivo immunomodulatory effect of L. gasseri LGV03 in zebrafish. (A) DiI-labeled Ect1/E6E7 cells (EC, red) were implanted into the yolk sac of zebrafish embryos, and different concentrations of L. gasseri LGV03 (1 × 106 CFU/mL, 1 × 107 CFU/mL) were added. Fluorescence intensity (B) and fluorescent area (C) of xenografted Ect1/E6E7 cells were analyzed quantitatively. Fluorescent microscopy images of Ect1/E6E7 cells in zebrafish xenografts at 0 h and 72 h. The results are presented as the mean ± SE (n = 5). one-way analysis of variance (ANOVA); **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to control.