Table 3.
Characteristics of patients with high vs low PAPi
| Characteristic | Low PAPi (N = 246) | High PAPi (N = 345) | P |
|---|---|---|---|
| Age, y, mean (SD) | 60.8 (16.34) | 61.9 (14.87) | 0.6326 |
| Female | 161 (65.4) | 231 (67.0) | 0.7019 |
| Etiology of PAH | 0.8547 | ||
| iPAH | 129 (52.4) | 168 (48.7) | |
| Heritable | 1 (0.4) | 2 (0.6) | |
| Drugs and toxins | 11 (4.5) | 9 (2.6) | |
| CTD | 78 (31.7) | 118 (34.2) | |
| CHD | 12 (4.9) | 21 (6.1) | |
| Portal hypertension | 7 (2.8) | 12 (3.5) | |
| HIV | 1 (0.4) | 3 (0.9) | |
| Low-risk functional class (1, 2) | 67 (27.2) | 114 (33.0) | 0.1311 |
| Height, cm, mean (SD) | 164.7 (9.95) | 164.8 (9.91) | 0.8999 |
| Weight, Kg, mean (SD) | 83.9 (25.19) | 75.5 (19.10) | 0.0003 |
| BMI, kg/m2, mean (SD) | 30.9 (8.89) | 27.7 (6.37) | < 0.0001 |
| Lung transplant | 2 (0.8) | 0 (0.0) | 0.0934 |
Values are n (%), unless otherwise indicated. PAPi is defined as pulmonary arterial pulse pressure divided by right atrial pressure.
BMI, body mass index; CHD, congenital heart disease; CTD, connective tissue disease; HIV, human immunodeficiency virus; iPAH, idiopathic PAH; PAH, pulmonary arterial hypertension; PAPi, pulmonary artery pulsatility index; SD, standard deviation.