Table 4.

Subgroup analysis for different types of telemedicine intervention.

Outcome	Computer-assisted dosing	Laboratory testing + remote adjustment	Self-testing	Multitasking application	P value for subgroup differences
Total thromboembolic events, RRa (95% CI)	0.92 (0.71 to 1.20)	0.46 (0.20 to 1.07)	0.90 (0.65 to 1.26)	0.20 (0.08 to 0.48)	.005
Major bleeding, RR (95% CI)	0.90 (0.75 to 1.08)	1.08 (0.80 to 1.45)	0.93 (0.70 to 1.23)	0.84 (0.36 to 1.98)	.77
Death, RR (95% CI)	1.05 (0.76 to 1.45)	1.27 (0.58 to 2.76)	0.84 (0.44 to 1.62)	0.62 (0.20 to 1.92)	.70
TTRb, MDc (95% CI)	2.19 (−0.44 to 4.81)	11.06 (−7.51 to 29.63)	3.24 (0.16 to 6.32)	7.00 (3.71 to 10.29)	.12

^aRR: relative risk.

^bTTR: time in therapeutic range.

^cMD: mean difference.