Figure 3.
Histological analysis of innate immune cell infiltration in LSG tissues. (A, B) Representative images of IHC staining for CK7, Bcl-2, CD45, CD21, CD68, Arginase-1 and CD56 in human LSGs in the control (A) and pSS (B) groups (scale bar = 100 μm). (C–E) Statistical analysis of the expression of cytokeratin 7 (CK7) (C), Bcl-2 (D) and CD45 (E) in human LSG tissues based on RNA-sequencing data (ns, no significant difference; *, p < 0.05; **, p < 0.01). (F) Monocyte infiltration and ssGSEA scores were compared between the two groups using the Mann–Whitney test (*, p < 0.05; **, p <0.01). (G) Statistical analysis of the expression of CD21 in human LSG tissues based on RNA-sequencing data. (H–J) Infiltration of M1 macrophages (H), M2 macrophages (I) and NK cells (J) and ssGSEA scores were compared between the two groups using the Mann–Whitney test (*, p < 0.05; **, p < 0.01).