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. 2023 Jul 24;6(7):e2324176. doi: 10.1001/jamanetworkopen.2023.24176

Table 3. Suggested Score Threshold Performancea.

Performance measure Suggested medium-risk threshold Suggested single threshold Suggested high-risk threshold
Goal Emphasize sensitivity Maximize F1 score (balance sensitivity and PPV) Emphasize PPV
Score threshold 37.4 63.9 68.3
F1 score, % (95% CI) 4.1 (4.0-4.1) 9.3 (9.3-9.3) 8.9 (8.8-8.9)
Sensitivity, % (95% CI) 50.2 (49.6-50.8) 10.8 (10.5-11.2) 7.9 (7.6-8.3)
Specificity, % (95% CI) 84.5 (84.5-84.6) 99.2 (99.2-99.2) 99.5 (99.5-99.5)
PPV, % (95% CI) 2.1 (2.1-2.1) 8.2 (7.9-8.4) 10.0 (9.6-10.4)
NPV, % (95% CI) 99.6 (99.6-99.6) 99.4 (99.4-99.4) 99.4 (99.4-99.4)
NNE 47.6 (46.6-48.1) 12.3 (11.9-12.7) 10.0 (9.6-10.4)

Abbreviations: NNE, number needed to evaluate; NPV, negative predictive value; PPV, positive predictive value.

a

Observation-level measures are shown (4 183 737 total predictions; deterioration prevalence of 0.7%).