Skip to main content
. Author manuscript; available in PMC: 2023 Jul 25.
Published in final edited form as: Mater Sci Eng C Mater Biol Appl. 2019 Aug 9;105:110070. doi: 10.1016/j.msec.2019.110070

Fig. 5.

Fig. 5.

Varshosaz et al. [75] applied Ecoflex® and PEG particles encapsulating docetaxel for the in vitro and in vivo treatment of ovarian cancer. (A) They prepared their particles by spraying into an aqueous phase containing a surfactant to stabilize and prevent coalescence of sprayed particles. Note the necessity of insulating the magnetic stirrer from the high voltage of the spray apparatus. (B) SEM micrograph of particles formed. (C) Presents cell viability in vitro where DTX refers to docetaxel, and NP nanoparticles.(D) The uptake of particles labeled with rhodamine B, as measured by flow cytometry, where M1 indicates autofluorescence of blank cells and the M2 region indicates greater fluorescence due to particle uptake. Each of the three particle groups in the M2 region were treated with rhodamine-loaded particles while the group in the M1 region was treated with unloaded particles. (E) Size of subcutaneous ovarian tumor with treatment of drug (Taxotere)-loaded particle, drug alone or with no treatment. (F) Body weight of each treatment group in E.