Table 6.
Electrospray technologies for treatment of inflammation and oxidative stress.
Polymer | Cargo | Axial | Particle size range | Cell model | Animal model | Ref |
---|---|---|---|---|---|---|
2-(40-N-dimethylamino-4-nitro- [1,1O-biphenyl] −3-yl)butane-l ,4-diyl dicarbonyl | Dexamethasone | Mono | 1 μm | RAW 264.7 macrophages | Carrageenan-induced hind paw inflammation (C57BL/6 mice) | [41] |
Ac-DEX PLGA | Dexamethasone | Mono | 3.3 μm | Cl 66 Endothelial cells C57B1/6 Bone-marrow derived macrophages | Dermal air pouch (inflammation model) Monosodium urate crystal (Gout) model | [110] |
PCL | Ganoderma lucidum polysaccharide | Tri | 13.37 μm | MRC-5 human lung fibroblasts | Pathogen-free KunMing mice | [111] |