Figure 6.

(A) Immunoblotting revealed a significant decrease in the expression of the SPC propeptide (Pro-SPC) in RAGE TG pup lungs treated with Dox from E0–E15.5 or E0–E16.5. * p ≤ 0.05 and ** p ≤ 0.01; blots were densitometrically normalized to β-actin and images are representative of three different immunoblotting experiments performed in quadruplicate. (B) Immunoblotting revealed significantly decreased elaboration of the mature SP-C protein when RAGE was induced from E0–E18.5 compared to controls. ** p ≤ 0.01; blots were densitometrically normalized to β-actin and images are representative of three different immunoblotting experiments performed in quadruplicate.