Table 2.

Implications of miR-483-3p in human diseases.

Type of Disease	Expression Pattern	Tissue	Cell Lines	Targets	Function	Refs
prediabetes/ type 2 diabetes	up	adipose	3T3-L1	GDF3	Induce lipotoxicity and insulin resistance	[69]
diabetic vascular disease	up	vascular endothelium, endothelial progenitor cells, cardiomyocytes	HAEC, H9C2	VEZF1 SRF1 IGF1	Induce apoptosis in cardiomyocytes and endothelial cells	[20,70,71,72]
cardiovascular disease, hypertension, aortic valve calcification	down	serum, heart/aortic valve endothelial cells, cardiomyocytes		TGF-β CTGF ACE1 ET1 UBE2C CDK9	Inhibit apoptosis, Protects endothelial function against inflammation	[73,74,75]