Table 2.

Host and viral factors that favor spontaneous HCV clearance following acute infection

Host factors
	Female [43-45]
	White ethnicity [46]
	Lack of HIV coinfection [46,47]
	HBV coinfection [48]
	Symptomatic (icteric) acute hepatitis [49,50]
	Intekeukin-28B rs12979860 CC and rs8099917 TT alleles [44,44,51-55]
	HLA class II DQB1*02, DQB1*03, DRB1*04, and DRB1*11 alleles [56]
	Vigorous HCV-specific T-cell response [50,57-59]
Viral factors
	HCV genotype 1 [44,60]
	High peak HCV RNA level [54,55]
	Limited diversity of HCV quasispecies [50,61-63]

HCV, hepatitis V virus; HIV, human immunodeficiency virus; HBV, hepatitis B virus; HLA, human leukocyte antigen; RNA, ribonucleic acid.