Table 5.

Endpoints for AIH treatment as proposed by the International Autoimmune Hepatitis Working Group after a consensus process

Endpoint	Definition
Complete biochemical response	Normalization of serum transaminases and IgG below the ULN within 6 months of treatment
Insufficient response	Lack of complete biochemical response. Should be determined no later than 6 months after initiation of treatment
Non-response	<50% decrease of serum transaminases within 4 weeks after initiation of treatment
Remission	Hepatitis activity index <4
Intolerance to treatment	Any adverse event possibly related to treatment as assessed by the treating physician leading to potential discontinuation of the drug

ULN, upper limit of normal range.