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ROC curve for CSF sTREM2 levels. The sensitivity and specificity of sTREM2 in CSF as a biomarker for AD were 65.81% and 80.00%, respectively. The best cut-off value was determined when the sum of sensitivity and specificity was maximized. This cut-off value is 23,950 pg/mL. AUC = 0.75; p < 0.0001. AD, Alzheimer’s disease; AUC, Area Under Curve; ROC, Receiver Operating Characteristic; sTREM2, sTREM2, soluble Triggering Receptor Expressed on Myeloid cells 2.
