Table 2.
Study characteristics.
| FIRST AUTHOR, YEAR | STUDY PERIOD | STUDY DESIGN | TISSUE | OBTAINING METHOD | ANALYSIS METHOD | QUALITY ASSESSMENT | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case-control | Cohort | Transcriptome meta-analysis | Animal | Peripheral blood | Eutopic endometrium | Ectopic endometrium | Peritoneal fluid | Menstrual effluent | |||||
| Ahn, 2016 | N/A | ✓ | ✓ | ✓ | Endometrial biopsy and laparoscopy | scRNAseq | Good | ||||||
| Bulmer, 1998 | N/A | ✓ | ✓ | ✓ | Unknown for endometriosis, hysterectomy for controls | IHC | Fair | ||||||
| Bunis, 2022 | N/A | ✓ | ✓ | Microarray data | GSEA | Good | |||||||
| Chen, 2017 | N/A | ✓ | ✓ | ✓ | Venepuncture and laparoscopy | FC | Fair | ||||||
| Correa, 2022 | 2013-2015 | ✓ | ✓ | Venepuncture and laparoscopy | FC | Good | |||||||
| D’Hooghe, 1996 | N/A | ✓ | ✓ | ✓ | Venepuncture and laparoscopy | FC | Good | ||||||
| Deng, 2022 | 2018-2019 | ✓ | ✓ | Laparoscopy | FC | Good | |||||||
| Gagne, 2003 | 1997–2001 | ✓ | ✓ | Venepuncture | FC | Good | |||||||
| Gallinelli, 2004 | 1999–2001 | ✓ | ✓ | Laparoscopy | FC | Poor | |||||||
| Gymrek, 2008 | N/A | ✓ | ✓ | Venepuncture | FC | Good | |||||||
| Ho, 1997 | 1993–1996 | ✓ | ✓ | ✓ | Venepuncture and laparoscopy | FC | Good | ||||||
| Hsu, 1997 | 1993–1994 | ✓ | ✓ | Venepuncture | FC | Good | |||||||
| Klentzeris, 1995 | N/A | ✓ | ✓ | Endometrial biopsy | IHC | Good | |||||||
| Li, 2019 | 2018–2019 | ✓ | ✓ | ✓ | Venepuncture and laparoscopy | FC | Good | ||||||
| Liu, 2020 | 2018–2019 | ✓ | ✓ | Venepuncture | FC | Fair | |||||||
| Ma, 2021 | N/A | ✓ | ✓ | ✓ | Endometrial biopsy and laparoscopy | scRNAseq | Fair | ||||||
| Mettler, 1997 | N/A | ✓ | ✓ | Endometrial biopsy | IHC | Good | |||||||
| Mier-Cabrera, 2011 | N/A | ✓ | ✓ | ✓ | Venepuncture and laparoscopy | FC | Fair | ||||||
| Muharam, 2022 | 2011 | ✓ | ✓ | Venepuncture | FC | Good | |||||||
| Opsahl, 1994 | N/A | ✓ | ✓ | ✓ | Venepuncture and laparoscopy | FC | Fair | ||||||
| Poli-Neto, 2021 | N/A | ✓ | ✓ | Microarray data | GSEA | Fair | |||||||
| Schmitz, 2021 | 2018-2019 | ✓ | ✓ | ✓ | Venepuncture and menstrual cup | FC | Fair | ||||||
| Shih, 2022 | N/A | ✓ | ✓ | Menstrual cup | scRNAseq | Fair | |||||||
| Sobstyl, 2020 | N/A | ✓ | ✓ | Venepuncture | FC | Fair | |||||||
| Wu, 2019 | N/A | ✓ | ✓ | ✓ | Venepuncture, laparoscopy and hysterectomy | IHC | Fair | ||||||
| Wu, 2021 | 2006-2013, 2016, 2018-2019 |
✓ | ✓ | ✓ | Microarray data, N/A | GSEA, IHC | Good | ||||||
| Zhong, 2021 | 2019 | ✓ | ✓ | ✓ | Microarray data | GSEA | Fair | ||||||
| Zou, 2021 | N/A | ✓ | ✓ | Laparoscopy | scRNAseq | ||||||||
N/A, Not available; scRNAseq, Single cell RNA sequencing; IHC, Immunohistochemistry; GSEA, Gene set enrichment analysis; FC, Flow cytometry.