Table 3.
Clinical symptoms with highest yield for cCMV infection.
| Indication for Testing | Symptoms Alone (n = 232) | All Indication (n = 465) | ||||
|---|---|---|---|---|---|---|
| Symptom | Newborns Tested | CMV+ | Newborns Tested | CMV+ | ||
| N | N | % | N | N | % | |
| Enlarged liver and/or spleen | 7 | 1 | 14.3 | 9 | 3 | 33.3 |
| Microcephaly | 16 | 1 | 6.3 | 32 | 3 | 9.4 |
| Growth impairment | 172 | 5 | 2.9 | 256 | 11 | 4.3 |
| Thrombocytopenia | 102 | 4 | 3.9 | 132 | 8 | 6 |
| Petechia | 8 | 1 | 12.5 | 12 | 4 | 33.3 |
| Hypotonia | 47 | 1 | 2.1 | 74 | 3 | 4 |
| Prematurity | 81 | 2 | 2.5 | 106 | 3 | 2.8 |
| Direct hyperbilirubinemia | 10 | 0 | 0 | 13 | 1 | 7.7 |
Growth impairment—includes newborns with intrauterine growth retardation (IUGR), small for gestational age (SGA), or low birth weight (LBW).