Table 2.

Regression modelling results, including slopes, significance levels and E-values for alcohol–cancer relationships.

Cancer	β-Estimate	Std. Error	p-Value	P. Adj. Holm	E-Value Estimate	Lower Bound E-Value
Oesophagus	0.1388	0.0059	5.92 × 10−108	2.43 × 10−106	1.80	1.75
All Cancers	0.0888	0.0069	3.72 × 10−34	1.12 × 10−32	1.85	1.74
Cervix	0.1395	0.0060	1.39 × 10−105	5.56 × 10−104	1.79	1.74
Prostate	0.0950	0.0048	1.12 × 10−78	4.36 × 10−77	1.70	1.64
Lung	0.0663	0.0036	3.94 × 10−69	1.50 × 10−67	1.66	1.60
All Cancers nNMSC	0.0456	0.0032	4.20 × 10−44	1.47 × 10−42	1.58	1.52
Kidney	0.0750	0.0054	3.29 × 10−42	1.12 × 10−40	1.54	1.48
Leukaemia—Lymphoid	0.0547	0.0091	4.19 × 10−09	9.63 × 10−08	1.61	1.46
Ovary	0.0652	0.0049	6.49 × 10−38	2.08 × 10−36	1.52	1.46
Stomach	0.0711	0.0064	1.65 × 10−27	4.62 × 10−26	1.45	1.40
Pancreas	0.0547	0.0051	2.34 × 10−26	6.31 × 10−25	1.45	1.39
Breast	0.0771	0.0104	1.82 × 10−13	4.72 × 10−12	1.34	1.28
Larynx	0.0332	0.0054	1.05 × 10−9	2.52 × 10−8	1.31	1.24
Leukaemia—Myeloid	0.0517	0.0163	0.0017	0.0284	1.38	1.21
Anus	0.0143	0.0038	0.0002	0.0036	1.25	1.16
Leukaemia	0.0305	0.0083	0.0003	0.0051	1.23	1.15
Corpus Uteri	0.0290	0.0080	0.0003	0.0061	1.22	1.14
Penis	0.0109	0.0038	0.0036	0.0542	1.21	1.11
Melanoma	0.0138	0.0059	0.0200	0.2398	1.17	1.06
Vulva and Vagina	0.0048	0.0044	0.2774	1.0000	1.12	1.00
Non-Hodgkin’s Lymphoma	0.0067	0.0046	0.1458	1.0000	1.13	1.00
Vulva	0.0104	0.0190	0.5831	1.0000	1.19	1.00
Oropharynx_Broad	0.0152	0.0166	0.3621	1.0000	1.20	1.00
Vagina	0.0151	0.0097	0.1221	1.0000	1.37	1.00
Colorectum	−0.0009	0.0036	0.7948	1.0000	1.05	-
Brain	−0.0113	0.0049	0.0216	0.2398	1.17	-
Non-Seminoma	−0.0316	0.4242	0.9411	1.0000	1.17	-
Testis	−0.0106	0.0043	0.0130	0.1825	1.19	-
Myeloma	−0.0172	0.0035	9.02 × 10−7	1.98 × 10−5	1.29	-
Hepatocellular	−0.0232	0.0170	0.1779	1.0000	1.41	-
Liver	−0.0749	0.0061	5.30 × 10−33	1.54 × 10−31	1.54	-
Bladder	−0.0678	0.0046	5.27 × 10−47	1.90 × 10−45	1.56	-
Hodgkin’s	−0.0425	0.0032	8.56 × 10−38	2.65 × 10−36	1.56	-
Gallbladder and Biliary	−0.0721	0.0053	8.46 × 10−39	2.79 × 10−37	1.60	-
Ovarian Dysgerminoma	−0.0102	0.0143	0.4840	1.0000	1.64	-
Kaposi	−0.0430	0.0179	0.0174	0.2260	1.65	-
Mesothelioma	−0.1087	0.0353	0.0024	0.0382	1.69	-
Oropharynx	−0.2054	0.0290	6.49 × 10−12	1.62 × 10−10	1.70	-
Thyroid	−0.1136	0.0063	3.01 × 10−66	1.11 × 10−64	1.72	-
Medulloblastoma	−0.0374	0.0272	0.1908	1.0000	2.43	-
Seminoma	−0.0882	0.0250	0.0011	0.0203	3.01	-

Table key: β-Estimate—estimate of the regression coefficient; Std. Error—standard error of the regression coefficient; p-value—significance level; P. Adj. Holm—p-value adjusted for multiple testing by the method of Holm; E-value—expected value required of some unknown confounder covariate with both the exposure and the outcome to explain the observed effect; lower bound of the E-value—the 95% lower bound of the confidence interval of the E-value.