. 2023 Jul 17;15(3):440–447. doi: 10.3390/hematolrep15030045

Table 1.

The analyses performed on the peripheral blood and the bone marrow at the diagnosis.

Analyses on Peripheral Blood
Complete blood count	WBC 0.87 × 10³/μL (neutrophils 0.47 × 10³/μL, lymphocytes 0.36 × 10³/μL, monocytes 0.04 × 10³/μL, eosinophils 0 × 10³/μL, basophils 0 × 10³/μL), PLTs 86 × 10³/μL confirmed on citrate, hemoglobin 12.4 mg/dL, MCV 93 fl, hematocrit 36%.
Blood tests	PT ratio 1.11, aPTT ratio 0.85 and fibrinogen 489 mg/dL, creatinine 0.9 mg/dL (eGFR 94 mL/min), sodium 138.6 mmol/L, potassium 4.45 mmol/L, calcium 2.37 mmol/L, glucose 121 mg/dL, AST 28 U/L, ALT 64 U/L, GGT 41 U/L, ALP 61 U/L, total bilirubin 0.7 mg/dL, LDH 214 U/L, uric acid 5.6 mg/dL, C-reactive protein (6.34 mg/dL), erythrocyte sedimentation rate 93 mm/h, iron 55 μg/dL, transferrin 204 mg/dL, ferritin 522 ng/mL, folic acid 16.6 ng/mL, vitamin B12 > 2000 pg/mL, D-dimer 14,187 ng/mL. Negative serological tests for HBV, HCV, HIV, EBV, and CMV.
Analyses on Bone Marrow
Flow cytometry	Big granular myeloid cells CD11b−, CD11c−, CD13+, CD33+, CD56−, CD117+, HLA-DR−, TdT−, and MPO+ amounting to 85% of cells, compatible with promyelocytes.
Histology	Cellularity of 80% to 90% characterized by an immature-looking myeloid population with oval nuclei and hypergranular eosinophilic cytoplasm. At the immunohistochemical assay, the cells showed intense and widespread positivity for MPO and weaker positivity for CD117, and they were negative for CD34, CD56, and TdT.
Molecular and cytogenetic analyses	Normal male karyotype at the cytogenetical analysis; presence of t(15;17) at the fluorescence in-situ hybridization (FISH); and PML-RARA fusion gene identified at the RT-PCR.