Table 3.

Randomized control trials comparing VET to SLT to guide coagulopathy management

Study	Patient population	Objective	VET assay	Inflection point
De Pietri et al23	Cirrhotic	Reduce prophylactic blood for procedure	Native TEG	R > 40 min = plasma
				MA < 20 mm = platelet
Rout et al49	Cirrhotic	Reduce blood product in variceal bleeding	Kaolin TEG	R > 15 min = plasma
				MA <30 min = platelet
Kumar et al24	Cirrhotic	Reduce blood product in nonvariceal bleeding	Kaolin TEG	R > 10 min = plasma
				Angle < 45° = fibrinogen
				MA < 55 mm = platelet
Zahr Eldeen et al47	Liver transplant	Risk stratify for HAT	Kaolin TEG	MA > 65 mm = postoperative risk
Nicolau-Raducu et al48	Liver transplant	Risk stratify for thrombotic event	Kaolin TEG	LY30 <0.9% = postoperative risk
Pustavoitau et al50	Liver transplant	Evaluate risk of intraoperative massive transfusion	Kaolin TEG	R > 6 min = risk for massive transfusion
Lawson et al51	Liver transplant	Evaluate risk of intraoperative massive transfusion	Native TEG	MA < 47 mm = risk for massive transfusion
Steib et al52	Liver transplant	Evaluate risk of intraoperative hyperfibrinolysis	Kaolin TEG	MA < 35 mm = risk for hyperfibrinolysis

Abbreviations: HAT, hepatic artery thrombosis; MA, maximum amplitude; R, reaction time; SLT, standard laboratory testing; TEG, thrombelastography; VET, viscoelastic testing.