TABLE 3.

Incidence of events and rate by baseline age class

Events	Age class (years)					All participants
	≤40	40–50	50–60	60–70	>70
Number at risk	2635	2028	2470	2263	2452	11848
Total person-years/1000	29.7	43.7	36.3	30.0	29.3	162.4
Total mortality
Number of deaths	42	102	322	736	1744	2946
Rate (per 1000 person-years)	1.18 [0.82–1.54]	3.29 [2.65–3.93]	8.87 [7.90–9.84]	24.5 [22.8–26.3]	59.5 [56.7–62.3]	18.1 [17.5–18.8]
Cardiovascular events
Number of events	26	89	283	502	1193	2093
Rate (per 1000 person-years)	0.73 [0.45–1.01]	2.87 [2.27–3.47]	7.80 [6.89–8.70]	16.7 [15.3–18.2]	40.7 [38.4–43.0]	12.9 [12.3–13.4]
CV mortality
Number of deaths	7	17	104	235	739	1102
Rate (per 1000 person-years)	0.20 [0.05–0.35]	0.55 [0.29–0.81]	2.87 [2.31–3.42]	7.83 [6.83–8.83]	25.2 [23.4–27.0]	6.79 [6.39–7.19]
Coronary events
Number of deaths	12	51	153	211	505	932
Rate (per 1000 person-years)	0.34 [0.15–0.53]	1.65 [1.20–2.10]	4.21 [3.54–4.88]	7.03 [6.67–7.39]	17.2 [15.7–18.7]	5.74 [5.34–6.11]
Stroke events
Number of events	10	30	99	232	475	846
Rate (per 1000 person-years)	0.28 [0.11–0.45]	0.97 [0.62–1.32]	2.73 [2.19–3.26]	7.73 [6.73–8.73]	16.2 [14.8–17.7]	5.21 [4.86–5.56]
Stroke mortality
Number of deaths	3	3	31	69	190	296
Rate (per 1000 person-years)	0.08 [−0.01 to 0.17]	0.10 [−0.01 to 0.21]	0.85 [0.55–1.15]	2.30 [1.76–2.84]	6.48 [5.56–7.41]	1.82 [1.52–2.03]

Data are rates given with 95% confidence interval calculated using the formulas shown in the Statistical Analysis section.