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. 2023 Jul 10;25:e46781. doi: 10.2196/46781

Table 2.

Group differences in depression and anxiety in the first 2 months of therapy.

Variable and group Baseline 1 Month 2 Months Effect sizes (95% CI) for effect baseline to 2 months Symptom reduction from baseline to 2 months (%) Time×group interaction effect—F test (df1, df2)
Depression (PHQ-9)a 2.66 (2,11)b

AIc 9.10 (4.70) 7.80 (4.26) 6.00 (2.56) 0.82 (–0.08 to 1.66) 34
TAUd 8.38 (4.34) 5.89 (4.34) 6.70 (5.54) 0.34 (–0.52 to 1.17) 20
Anxiety (GAD-7)e 2.89 (2,11)b

AI 8.30 (3.95) 6.60 (3.78) 5.88 (1.89) 0.78 (–0.11 to 1.62) 29
TAU 7.63 (3.70) 5.89 (4.34) 7.00 (5.21) 0.14 (–0.70 to 0.97) 8

aPHQ-9: Patient Health Questionnaire-9.

bNot significant.

cAI: artificial intelligence.

dTAU: treatment as usual.

eGAD-7: Generalized Anxiety Disorder-7.