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. 2023 Jul 5;63(2):97. doi: 10.3892/ijo.2023.5545

Figure 4.

Figure 4

Mechanism of (A) immune checkpoint inhibitors (CTLA-4, PD-1 and PD-L1 inhibitors) and (B) adoptive cell transfer of cytotoxic T lymphocytes. The figure was created with BioRender. MHC, major histocompatibility complex; TCR, T-cell receptor; CTLA-4, cytotoxic T-lymphocyte-associated antigen-4; PD-1, programmed cell death protein-1; PD-L1, programmed death ligand-1; EBV, Epstein-Barr virus; LCL, lymphoblastoid B-cell line; CTLs, cytotoxic T-lymphocytes; PBMCs, peripheral blood mononuclear cells.