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. 2023 Jul 12;25(28):5297–5301. doi: 10.1021/acs.orglett.3c01849

Table 1. Optimizing C–O Cross-Coupling of (E)-Vinylic Iodide 5 with Alcohol 8 to Give (E)-Vinylic Ether 9.

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a

o-Xylene solvent at 120 °C in entry 1; tetraglyme solvent at 75–80 °C in entries 2–3; and DME solvent in entries 4–7.

b

Produced 1.05 g (2.6 mmol) of (E)-vinylic ether 9.

c

With (E)-1-bromo-1-decene (1 equiv).