. 2023 May 8;62(20):7932–7953. doi: 10.1021/acs.inorgchem.3c00753

Table 9. IC₅₀ Values (μM) Calculated for the Ligand Precursors and Corresponding Vanadium Complexes Against the HT-29, HeLa, and NIH-3T3 Cells Upon 48 h of Exposure^a.

complex	HT-29	selectivity index (SI)	HeLa	selectivity index (SI)	NIH-3T3
H₂L¹	14.7 ± 0.6	1.6	15.7 ± 1.9	1.5	23.5 ± 0.6
1	7.2 ± 0.6	1.2	9.3 ± 0.2	0.9	8.7 ± 1.1
H₂L²	17.9 ± 0.8	1.3	16.5 ± 1.4	1.4	23.1 ± 2.3
2	6.1 ± 2.0	2.2	8.2 ± 0.2	1.6	13.3 ± 1.3
H₂L³	12.6 ± 2.1	>4	6.3 ± 0.1	>8	>50
3	16.2 ± 0.4	0.6	11.1 ± 0.9	0.9	10.3 ± 2.2
H₂L⁴	13.1 ± 3.2	3.7	7.5 ± 0.3	6.6	49.2 ± 1.6
4	18.7 ± 1.6	0.6	17.1 ± 0.1	0.7	11.4 ± 3.1
cisplatin^b	32.7 ± 0.6		25.5 ± 0.8

Results are the mean ± SD of two independent experiments done with four replicates.

Data taken from refs (79) and (148).

Table 9. IC50 Values (μM) Calculated for the Ligand Precursors and Corresponding Vanadium Complexes Against the HT-29, HeLa, and NIH-3T3 Cells Upon 48 h of Exposurea.